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Dose Confirmation: In another placebo-controlled, multi-site clinical trial, clomipramine hydrochloride tablets at 2 - 4 mg/kg/day given either once daily or divided twice daily showed significant improvement in resolving signs of separation anxiety when tested against behavioral modification alone (desensitization and counterconditioning)

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Morphine was particularly weak in its ability to promote multisite phosphorylation within the Thr370 through Thr379 region