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Pharmacokinetics and absolute bioavailability of mepolizumab following administration at subcutaneous and intramuscular sites - Ortega - 2014 - Clinical Pharmacology in Drug Development - Wiley Online Library

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304 In tamoxifen-resistant ER (+) breast tumors, KDM5A can activate IGF1R and ErbB signaling, causing the activation of PI3K/AKT/mTOR pathway and leading to the occurrence of tamoxifen resistance (Fig