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These investigations provide insights into the metabolic regulation of contractile adaptation and the cellular mechanisms underlying activity-induced metabolic remodeling in muscle tissue across different experimental conditions

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Rosiglitazone increased luciferase activity of pGL3BV- PPARGC1A -1631 (Figure 4C), while it did not have any effect on pGL3BV- PPARGC1A -1386 (Figure 4D), pGL3BV- PPARGC1A -1012 (Figure 4E), and pGL3BV- PPARGC1A -210 (Figure 4F)