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Leaf samples were collected at 1, 5, 10, 15, and 18 days after stress treatment, rinsed with RNase-free water, flash-frozen in liquid nitrogen, and stored at −80°C until further analysis

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Circulating IGF1 level plays a significant role as a risk factor for the onset and development of various tumors by the increase of neoplastic cell proliferation, such as lung, breast, ovarian and colorectal cancers (Myal et al., 1984