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Second, it is the only known neuropeptide whose gene and specific receptor have not been identified despite 50 years of research — which makes it a uniquely compelling tool for studying neuropeptide pharmacology mechanisms independent of classical receptor binding assays

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[DOI] [PubMed] [Google Scholar] 51.Rothstein J.D., Dykes-Hoberg M., Pardo C.A., Bristol L.A., Jin L., Kuncl R.W., Kanai Y., Hediger M.A., Wang Y., Schielke J.P., et al