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it drives metabolic chaos: Hormonal imbalance : Androgen dominance post-estrogen decline promotes fat storage.[1] Inflammatory cascade : Visceral fat spikes CRP and leptin while suppressing adiponectin, escalating cardiovascular risks.[2] Insulin resistance : Estrogen loss impairs glucose metabolism, creating a vicious cycle of weight gain and metabolic dysfunction.[3] GLP-1 Agonists: Benefits and Mechanisms These medications remain valuable tools: Appetite regulation : They mimic GLP-1 to slow gastric emptying and enhance satiety