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Growth factors (GF), coagulation factors, adhesion molecules, cytokines, chemokines, and integrins are all stored in platelets ( Figure 1 )

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In the hypertensive kidney injury model, tissue transglutaminase (TG2) modifies AT 1 R through isopeptide bonds, causing its accumulation and heightened sensitivity to angiotensin II, thus contributing to the model’s pathological processes, whereas the TG2 inhibitor ERW1041E can ease related symptoms (Liu C