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Tran PHT, Malmgaard-Clausen NM, Puggaard RS, Svensson RB, Nybing JD, Hansen P, Schjerling P, Zinglersen AH, Couppé C, Boesen M, Magnusson SP, Kjaer M

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Chrysin (CN), a flavonoid extracted from Passiflora caerulea L., ameliorates hepatic lipid metabolic disorders by activating AMPK and modulating lipid metabolism-related proteins (e.g., SREBP1-c and ACC), while also suppressing the NLRP3/Caspase1 pathway to reduce pro-inflammatory cytokines (IL-1β, IL-6, TNF-α, IL-17), thereby counteracting NAFLD (Wu D