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4.3 Obesity There exists a reciprocal promotional relationship between OSAHS and obesity, wherein OSAHS exacerbates endocrine dysfunction, thereby worsening obesity in individuals with obesity (145)

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Overall, our study provides epigenetic evidence of epithelial-intrinsic trained immunity caused by a mucosal bacterial infection, which alters the bladder mucosal response to subsequent infections, depending on the original disease outcome