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10.3389/FIMMU.2019.02546/PDF [DOI] [PMC free article] [PubMed] [Google Scholar] Yang Y, Wang X, Xiao A et al (2022) Ketogenic diet prevents chronic sleep deprivation-induced Alzheimer’s disease by inhibiting iron dyshomeostasis and promoting repair via Sirt1/Nrf2 pathway

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Impaired mitochondria can be improved by fusing with healthy mitochondria, however, severely damaged ones are isolated from healthy mitochondria by division and then targeted for degradation by mitophagy as described earlier [130, 131]