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The signaling pathways triggered by IL-4 and IL-13 recruit two distinct heterodimeric IL-4 receptors, type I IL-4R (comprising IL-4Rα and the γc common cytokine receptor chains) and type II IL-4R (comprising IL-4Rα and IL-13Rα1 chains)

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Proactive monitoring of both B12 and glycaemic status — particularly in higher-risk groups — is the most effective way to ensure that neither condition is inadvertently overlooked or mismanaged