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For example, some studies have found that the secondary mutations of D1228N/V and Y1230C in the MET kinase domain are the main mechanisms for acquired resistance to crizotinib in METex14 patients receiving c-MET inhibitor treatment [149, 150]

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Style:Single Session

In human beings, this substance is widely distributed in the various organs and tissues, with the maximum concentration in the liver, followed by the spleen and kidneys