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104 NOX and Neurodegeneration To maintain homeostasis and neuronal cell function, the human nervous system consumes about 20% of the amount of oxygen used by the body, causing a large production of ROS

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Some compounds that protect hair cells from aminoglycoside exposure, for example tacrine and other quinoline ring-containing structures, do so by inhibiting aminoglycoside uptake (Ou et al., 2009, 2012)