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This genetic variability influences a person’s susceptibility to developing alcoholism and alcohol-related tissue damage

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We then shifted to our mouse model of PCBP1 depletion, which relies on a tamoxifen-inducible Cre- loxP system with PCBP1 flanked by loxP sites and a transgene carrying the Cre recombinase-estrogen receptor (Cre-ER T2 ) fusion protein (Ryu et al., 2017)