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Patients with known or presumed hypersensitivity to any component of the ophthalmic preparations (active substances or excipients), and those treated with drugs that could interfere with this trial, were also excluded from the study

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Cystine moieties are transported into brain as (i) γ-glutamylcystine or as (ii) cystinylbisglycine which are possible origins of GSH in brain [21]