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For instance, TNF-α can induce the production of IL-6 and IL-1β, which in turn perpetuate inflammation by activating downstream signaling pathways such as nuclear factor-kappa B (NF-κB) (Brasier, 2010)

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Withhold PEMFEXY for acute onset of new or progressive unexplained pulmonary symptoms such as dyspnea, cough, or fever pending diagnostic evaluation