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In this method, nitrite is neutralized with ammonium sulfamate [50] to avoid artifactual formation of S-nitrosothiols at low pH, and samples are analyzed by HPLC

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Thus, mitochondrial protein adduct formation, oxidative stress, and, ultimately, induction of the MPTP are central to APAP-induced liver injury, and it is now evident that the organelle also plays a significant role in the recovery and regeneration process after injury

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