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Knockdown of BRAF gene expression (Supplementary Figure 1A) sensitized HT29 (BRAF V600E ) cells to cetuximab treatment (Fig

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Converting those to the units products are sold in is revealing: There is a legitimate reason a topical product is not formulated at 10⁻⁹ M: a molecule applied to intact skin must cross the stratum corneum, and only a fraction of what is applied reaches living tissue