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In the duodenum, this freed vitamin B12 combines with intrinsic factor (IF), a transport and delivery binding protein secreted by the stomach’s parietal cells and this complex is absorbed in the distal ileum by cubum receptor-mediated endocytosis

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As the preeminent open access database for post-marketing pharmacovigilance, the FAERS database provides a significant advantage in identifying potential red flags for infrequent adverse reactions, including HE ( HE, a recognized adverse effect of VPA and its derivatives, is well known in clinical settings