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Symptoms of Parkinson’s Disease Parkinson’s disease can present with a wide range of motor and non-motor symptoms, including: Tremor (often starting in one hand or limb at rest) Stiffness or rigidity in the limbs or trunk Slowness of movement (bradykinesia) Postural instability or balance problems Sleep disturbances Mood changes such as depression or anxiety Cognitive changes or memory decline Causes and Risk Factors The hallmark feature of Parkinson’s disease is the progressive loss of dopamine-producing neurons in a brain region called the substantia nigra

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