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(90) showed that UDCA and chenodeoxycholic acid attenuate endotoxin-induced lung injury in rats by regulating aquaporin 1 and aquaporin 5 to maintain water balance, reducing oxidative stress in alveolar epithelium, modulating apoptosis-related proteins (BAX, caspase-3, BCL-2), and inhibiting NF-κB-driven cytokine release
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Advantages include: Better protection from gastrointestinal breakdown Improved bioavailability versus standard formulas Enhanced cellular uptake Reliable daily antioxidant support Strong tolerability over extended use These mechanisms line up with the positive trends seen across energy, skin, and digestion in this trial