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It can present with skin reactions of dermatitis, acneiform eruption, dry skin, pruritus, photosensitivity, or hand-foot skin reactions in 28% to 71% of 30 patients

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The lack of interactions of P37 Cagri with RAMP 1 and 3 is consistent with the ability of Cagri to form high-affinity interactions with the CTR protomer alone (Fig