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According to a 2007 randomized controlled trial in the New England Journal of Medicine, visceral adipose tissue decreased by 15.2 percent in the tesamorelin group while increasing by 5.0 percent in the placebo group over 26 weeks, alongside improvements in triglycerides and cholesterol ratios, with no significant adverse effect on glucose control

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Clinically, it is mostly used to decrease fine lines and wrinkles and to improve hair regrowth feedback signal that is generated after tissue injury