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DAMPs activating innate and adaptive immune responses in COPD

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Strong suppression of the anti-sheep erythrocytes plaque-forming cell response, the mixed lymphocyte response, and the graft-versus-host response in vivo were seen in the progeny of female mice that had been treated intraperitoneally with benzo [a] pyrene at a dose of 150 mg/kg bw during mid-gestation (11-13 days)