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Specifically, the FDA warns that compounded drugs containing Selank pose a risk for immunogenicity, a state in which the body perceives a substance as a threat and mounts a potentially life-threatening immune response against it.21 22 The FDA qualifies the risk to “certain routes of administration” but doesn’t specify which routes, and also notes a lack of safety information concerning Selank administered to humans.21 Our relationships with peptide providers have given us additional insights into this topic, but the side effects they’ve shared with us are no different from those of most therapeutic peptides we’ve covered ( injection site reactions , stomach discomfort , nausea , headaches , and dizziness )
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in addition, SDS inactivates HRP 23 and urea denatures HRP 24,25 , which render the assay unreliable