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NAC is one of those compounds that exposes how little we’re taught to think in systems., Yes, it supports glutathione synthesis — but clinically, its impact on ammonia clearance and glutamate ...

10.1016/s0027-5107(02)00317-2 [DOI] [PubMed] [Google Scholar] Arouna, N., Gabriele, M., & Pucci, L

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presented a work based on organoid‐derived proximal tubule epithelial cells (OPTEC)-on-chip, providing a more sensitive predictor of nephrotoxicity compared to traditional models based on immortalized PTECs (166)