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These sex-related differences in oxidative stress are consistent with prior findings that suggest males are more susceptible to oxidative damage, which has been associated with the development of neurodegenerative disease risk [77]

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siRNA-mediated dynamin knockdown siRNA transfection The neurons were co-transfected with 50 nM dynamin 1, 2, and 3 siRNA constructs (previously described in 65 ) or with non-targeting control siRNA (ON-TARGETplus Non-targeting Control Pool