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The emerging data surrounding lenacapavir is so astonishing that the drug's development has been heralded as the 2024 Breakthrough of the Year by the journal Science, which described it as representing "a pivotal step toward diminishing HIV/AIDS as a global health crisis." PURPOSE 2, a study sponsored by Gilead Science, the California-based maker of lenacapavir, found the drug to be 96% effective in preventing HIV infections in the newly released results of a clinical trial of more than 3,200 cisgender men, transgender men, transgender women and gender non-binary individuals who have sex with partners assigned male at birth
