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127 Since SA signaling is closely interconnected with other hormonal pathways, particularly JA, strategies that increase SA (for example sustained‐release formulations) risk disrupting the balance between defense programs

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Practical considerations for safety and consistency: 🟠 Use a new sterile insulin syringe for every injection 🟠 Rotate injection locations to reduce local irritation 🟠 Inject slowly and wait briefly before removing needle 🟠 Track daily dosing and site rotation for consistency 🟠 Human clinical evidence remains limited