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An assay based on the blockade of ovulation in cycling rats was used for testing antagonists 19 , and analogs such as [d-Phe2, d-Ala6]-LH-RH and [d-Phe2, d-Leu6]-LH-RH were able to block ovulation and the preovulatory surge of gonadotropin 19

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Function Choline and compounds derived from choline (i.e., metabolites) serve a number of vital biological functions ( Figure 1 ) (1)