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Through blocking the Wnt/β-catenin signaling pathways, vitamin C has been found to promote bone regeneration ( 4.6 Liver and kidney functions and histopathological findings Approximately 30% of the LZD is excreted unchanged by the kidneys, while the rest is metabolized by oxidizing its morpholine ring, which is facilitated by ROS using NADPH in the liver (Wynalda et al., 2000), resulting in the creation of two metabolites: amino-ethoxy-acetic-acid and hydroxyethyl glycine ( The present study showed that linezolid-induced liver damage was demonstrated by an increase in the marker enzymes alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT)