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Keywords: GHK-Cu, acute lung, injury, inflammation, NF-κB p65, p38 MAPK INTRODUCTION Acute lung injury (ALI), along with its most severe form, acute respiratory distress syndrome (ARDS), is a disorder of acute inflammation and tissue injury that is characterized by the loss of alveolar-capillary membrane integrity, excessive transepithelial neutrophil migration, and the release of pro-inflammatory and cytotoxic mediators [1, 2]
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Similarly, other randomized clinical trials are currently ongoing to investigate the efficacy of tirzepatide in improving glucose control and reducing body weight in adults with T1D and overweight/obesity (ClinicalTrials.gov ID: NCT06180616) [148], as well as the role of tirzepatide as an adjunct to AID in adults with T1D (ClinicalTrials.gov ID: NCT06630585) [149]
