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Treating the lack of nutrition through diet, lifestyle changes, and possibly the addition of supplements could help these individuals

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The vasculoprotective effects of endogenous Tβ4 that we report appear to be mediated, at least in part, via control of LRP1–PDGFR-β exposure on the cell surface to influence the sensitivity of VSMCs to PDGF-BB and potentially other ligands regulated by LRP1 (71)