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In these cells, the GSH levels were significantly higher than those in A2780 cells (Figure 3 and Figure 4) and the drastic decrease in GSH by glutamate, a competitive inhibitor of the cystine uptake, indicates that system x c − mainly contributes to the high level of GSH in A2780DDP cells

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[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Olasehinde T.A., Olaniran A.O., Okoh A.I