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Cellular studies have shown that exogenous NAD + can impact mitochondrial activity, such as boosting Krebs cycle and the ETC, but also impair genomic DNA replication and induce DNA replication stress due to impairment of pyrimidine biosynthesis 118

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Week 7–8: Add 5-Amino-1MQ (5mg/day to start, increase to 10–25mg/day based on tolerance) Running simultaneously (established protocol): If you're already on GLP-1 therapy and want to add the full stack, all four can be added simultaneously