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Research applications NNMT enzyme inhibition and adipocyte metabolism research Cell-culture studies of methylation capacity and NAD+ salvage Rodent models of diet-induced adiposity Small-molecule structure-activity research in the quinolinium class What the literature reports on 5-Amino-1MQ NNMT catalyses the transfer of a methyl group from S-adenosylmethionine to nicotinamide, a reaction that has been reported to influence both cellular methylation capacity and the availability of nicotinamide for NAD+ salvage synthesis