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Structural ubiquitin contributes to K48 linkage specificity of the HECT ligase Tom1: Cell Reports

Peli3 deficiency diminishes mitochondrial translocation and phosphorylation of GSK3β upon APAP treatment Our present findings strongly indicate that Pellino3 acts as an E3 ligase to induce the polyubiquitination of GSK3β

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“Everybody kind of knew they were doing something a little mad scientisty,” one Reddit user told Undark in a Zoom interview