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Using Patch-seq to simultaneously measure electrophysiological properties and the transcriptome of individual beta cells, Camunas-Soler et al [29] identified gene sets associated with functional heterogeneity in non-diabetic donors, where expression of FAM159B and RBP4 correlated positively and negatively with exocytosis, respectively

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These changes may affect immune responses, natural growth hormone cycles, and overall endocrine function