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Not all anti-inflammatory peptides work the same way. GLP-1 receptor agonists anchor the list for their broad effect on insulin resistance, a primary driver of systemic inflammatory burden. BPC-157 supports local tissue

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By activating the Nrf2 pathway, it disrupts iron accumulation, lipid peroxidation, and ferroptosis, preventing the downregulation of GSH and GPX4 levels, thus ameliorating cisplatin-induced AKI (183)