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G6PD Deficiency • Glucose-6-phosphate dehydrogenase deficiency • X-linked recessive disorder • Leads to low NADPH, impairing glutathione regeneration → RBCs are vulnerable to oxidative damage ⸻ Pathophysiology: In G6PD deficiency: • No

Xu, S.-F., et al., α-Lipoic acid improves abnormal behavior by mitigation of oxidative stress, inflammation, ferroptosis, and tauopathy in P301S Tau transgenic mice

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