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Along with muscular weakness, there was progressing intracranial (sinus sagittal superior), portal and caval hypertension, and aortal hypotension, progressing thrombosis, in arteries and veins, both peripherally and centrally, severe ECG disturbances, and severe lesions in the brain, heart, lung, liver, kidney and gastrointestinal tract [80]

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doi: 10.1016/j.jmb.2006.08.062