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A three-peptide stack with each component at functional concentration outperforms a six-peptide blend where four compounds appear at trace amounts added primarily for label claims

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64 HDAC2 loss leads to the accumulation of acetylated histones on inflammatory gene promoters (IL-8, TNFα, etc.), driving persistent inflammation and conferring steroid insensitivity since corticosteroids require HDAC2 to repress gene transcription