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Taken together, all the above experimental observations indicate that by promoting oxidative damage and inflammation in the CNS, exacerbating excitotoxic damage by (i) increasing the levels of excitotoxic mediators and (ii) impeding their clearance, aluminum can both trigger and promote neuronal injury

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With some selected phytochemical combinations (resveratrol, quercetin, epigallocatechin-3-gallate, and piperine), Curcumin exerts synergistic effects in cancer treatment to improve its clinical efficacy [37]